Objective : To evaluate the efficacy of subcutaneous morphine for postoperative analgesia comparing with intramuscular morphine.Materials and Methods : The randomized controlled study was conducted in Hatyai hospital. The 60 conxecutive healthy gynecological patients undergoing the explor - laparotomy were randomly divided into 2 groups to receive either intramuscular morphine (group 1) or subcutaneous morphine with an indwelling small intravenous cannula (group 2) on request four-hourly for postoperative analgesia. They were interveiwed and evaluated at time of administration and after 1 hour in pain, sedation and nausea score as well as respiration rate.Results : There were no signicicantely differenced in pain, sedation and nausea score as well as respiratory rate between subcutaneous and intramuscular morphine.Conclusion : Intermittent subcutaneous morphine with and indwelling cannula would be an alternative to intramuscular morphine for postoperative analgesia. The advantage of using this route is to improve patient comfort as the number of skin puncture is decreased.