Objective: This study aimed to compare total drainage volume between patients underwent total mastectomy using traditional electrosurgery and low thermal tissue dissection system.

Materials and Methods: This is randomized controlled trial included total 50 patients who underwent mastectomy at Division of Head Neck Breast Surgery Siriraj Hospital. Twenty-five patients received traditional electrosurgery system during mastectomy whereas twenty-five patients received low thermal tissue dissection system (PEAK Plasmablade®). Total seroma volume, drainage duration, estimated blood loss, operative time, post-operative hospital stay, pain score, number of aspiration post tube drain removal and other post-operative complications were recorded and were compared between two group using SPSS Statistics for Mac version 21.

Results: Average age in the traditional electrosurgery (control) group was 59.32+2.09 years and was 60.44+2.09 years in the low thermal dissection (experimental) group. Overall, both groups had similar types of operation. Median drainage volume was 590 ml in the traditional electrosurgery group and 790 ml in the low thermal dissection group. The median drainage duration in the traditional electrosurgery group was 4 days which were similar to the low thermal dissection group.

Conclusion: The low thermal tissue dissection system demonstrated no superior advantages compared with the traditional electrosurgery system in mastectomy patients.