Background: Hemodynamic change during induction of anesthesia and intubation is very crucial particularly in high risk patients. Variety of videolaryngoscopes have been currently launched to provide a good glottic visualization which allows less pressure on the laryngeal area. Aim of this study is to compare the hemodynamic effect of C-MAC videolaryngoscope with conventional direct laryngoscope.

Methods: This prospective, double-blinded, parallel group, randomized controlled trial enrolled 114 normotensive patients who underwent elective surgery that required orotracheal intubation. They were randomly allocated into two groups which were 57 patients equally for direct laryngoscope (DL) and C-MAC video laryngoscope (C-MAC). Mean arterial pressure (MAP) and heart rate (HR) were measured before induction (baseline), after induction (T₀), after intubation (T₁), and then every minute for five minutes following intubation. Other intubating parameters were recorded.

Results: No significant difference in mean difference MAP and HR were detected for both groups. Intubation time was significantly faster in direct laryngoscope group (14.6±4.4 seconds) when compared with C-MAC group (18.9±6.3 seconds) p<0.001. The occurrence of postoperative sore throat was lower in C-MAC group (7%) with a statistically significant difference (p=0.021).

Conclusions: There was no benefit of using C-MAC videolaryngoscope for intubation in terms of hemodynamic stability, but C-MAC videolaryngoscope should be considered advantageous over DL for attenuating risk of postoperative sore throat.