A cost-effectiveness analysis of national smoking cessation services among chronic obstructive pulmonary disease patients in Thailand
Ratthanon Prasitwarachot, Kednapa Thavorn, Chanthawat Patikorn, Somkiat Wattanasirichaigoon, สุทัศน์ รุ่งเรืองหิรัญญา, Araya Thongphiew, ณธร ชัยญาคุณาพฤกษ์*
Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA;j IDEAS Center, Veterans Affairs Salt Lake City Healthcare System, Salt Lake City, UT, USA; Email: [email protected]
Aims: Thailand’s national smoking cessation services (FAH-SAI clinics) were founded in 2010. A cost-effectiveness analysis (CEA) is needed to inform policymakers of the allocation and prioritization of the limited budget to maximize the value for money of reimbursing these services. Chronic obstructive pulmonary disease (COPD) patients would benefit from smoking cessation services. Therefore, this study aimed to assess the cost-effectiveness of these multidisciplinary services compared to the usual care among COPD patients in Thailand from a societal perspective.
Methods: We conducted a CEA from a societal perspective using a Markov model to simulate lifetime costs and quality-adjusted life years (QALYs) gained by each smoking cessation intervention over the patient’s lifetime. We derived the effectiveness of the smoking cessation services from a multicenter, longitudinal study of smoking cessation services in Thailand and estimated the natural quit rate, transition probabilities, health utility, and cost data from the published literature. Costs and outcomes were discounted at 3%. Sensitivity analyses were performed.
Results: Compared to the usual care, FAH-SAI clinics were associated with higher costs (4,207 THB (US$133)) and improved QALYs (0.11), with an incremental cost-effectiveness ratio of 37,675 THB/QALY (US$1,187/QALY). The effectiveness of FAH-SAI clinics was a key driver of the cost-effectiveness results. At the willingness-to-pay (WTP) threshold of 160,000 THB (US$5,042) per QALY gained, the probability of being cost-effective was 96.5%.
Conclusions: FAH-SAI clinics were cost-effective under Thailand’s WTP threshold. Our results could inform policymakers in allocating resources to support smoking cessation services for COPD patients in Thailand.
Journal of Medical Economics ปี 2566, ปีที่: 26 ฉบับที่ 1 หน้า 1377-1385
Thailand, Cost-effectiveness analysis, Smoking cessation, Economic evaluation, chronic obstructivepulmonary disease