Objective: To assess the quality of life (QOL) and related factors in psoriatic patients.

Materials and Methods: A cross-sectional study was conducted of 145 out-patients with psoriasis in Rajavithi Hospital. SF-36 mean scores were recorded for eight dimensions, physical function (PF), role limitations due to physical problems (RP), role limitations due to emotional problems (RE), vitality (VT); bodily pain (BP), general health (GH), social function (SF), and mental health (MH). The relationships between factors and QOL were explored using Pearson’s correlation coefficient.

Results: The mean age was 46.27±16.25 years, and 55.2% were male. Average BMI was 25.40±5.45 kg/m², and the mean duration of psoriasis was 48 months. The median PASI score was 10, and 62% had a PASI score of 10 or less. The main areas of involvement were skin (77.2%), scalp (59.3%), and nails (44.8%). The QOL scores ranged from 35.67 to 72.00 with the highest score for bodily pain (72.00±21.86), followed by physical role (71.90±36.67), and emotional role (67.82±37.56). Female, smoking, underlying diseases, and area of involvement were associated with QOL.

Conclusion: Demographic, behavioral, and psoriasis-specific factors are associated with QOL.